What is Lyophilized Cartilage ( lyophilized cartilage )? Lyophilized cartilage also called freeze-dried cartilage comes from the rib bones of organ donors and is an ideal bone substitute material. Lyophilized cartilage was developed and studied experimentally in 1976/77 by Professor Sailer at the Royal College of Surgeons of England. Lyophilized cartilage has no antigenicity, which meens it will not be rejected, it shows the lowest infection rate of all bone substitute materials and it builds itself up in patient's own bone to what might be called " biological miracle." Professor Sailer uses it in reconstructive craniofacial surgery in pathological and aesthetic problems .
Hundreds of thousands of implantation of lyophilized cartilage were applied at the University Hospitel in the department of Oral- and Maxillofacial Surgery, where Professor Sailer was clinic director as well as many other university hospitals and institutes worldwide . The advantage of lyophilized cartilage is that there is no need for removing patient’s own material such as cartilage or bone, thus has a second surgical spared with possible complications and also shortens the operation time. Lyophilized cartilage can also be used in an infected area, is resistant to infection, easy to use and is, for example, with reconstructions for infants available in greater quantity than the patient's own cartilage-bone material.
Professor Sailer's most common uses of lyophilized cartilage in aesthetic surgery are : zygomatic bone, zygomatic arch and augmentations of the middleface areas , nose , chin enlargement , relining deeper nasolabial folds and labiomental fold . In reconstructive craniofacial surgery there are the following applications: Reconstruction of the cranial vault , construction of the forehead region, reconstruction of orbital walls, correction of the nostrils collapse, filling bone cysts and the chronically infected sinus, as well as bridging defect in cleft lip and cleft palate and many more . Professor Seiler wrote about this material and its applications more than 30 scientific papers as well as a monograph with the title: Transplantation of Lyophilized Cartilage in Maxillo-Facial Surgery, Experimental Foundations and Clinical Success. Karger 1983